cytotoxic T cell

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cytotoxic T cell

[¦sīd·ə‚täk·sik ′tē ‚sel]
(immunology)
A type of T cell which protects against pathogens that invade host cell cytoplasm, where they cannot be bound by antibodies, by recognizing and killing the host cell before the pathogens can proliferate and escape.
References in periodicals archive ?
Once the epitope candidates selected by this method are confirmed in cytotoxic T-cell (CTL) assays, they may be useful for 1) screening exposed persons for T-cell responses, 2) investigating the immunopathogenesis of WN virus disease in humans, 3) as components of diagnostic kits developed for WN virus surveillance, 4) as reagents for measuring WN virus vaccine-related immune responses, and possibly 5) as components of a subunit vaccine for WN virus.
Primary Cutaneous CD8-Positive Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma: [CD3.
An ultrastructural study of cutaneous panniculitis-like T-cell lymphoma: cytoplasmic granules and active cellular and cell-to-matrix interaction mimic cytotoxic T-cells.
Polyclonal or oligoclonal expansion of cytotoxic T-cells often occurs early In the disease process in HIV-positive patients.
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