decarboxylate


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decarboxylate

[‚dē·kär′bäk·sə‚lāt]
(organic chemistry)
To remove the carboxyl radical, especially from amino acids and protein.
References in periodicals archive ?
Both strains were the same phage type, were indistinguishable by plasmid profile typing, and were different from 97% of salmonellae (8) in that they did not decarboxylate lysine.
Both have the ability to take up and decarboxylate amine precursors.
During our investigations to develop a convenient three-step one pot synthesis of N-H pyrazoles, we explored the possibility of dilithiation of several C([alpha]),N-carbobenzyl-oxyhydrazones and related carboalkoxyhydrazones and their condensation with select esters, followed by acid hydrolysis to the pyrazole N-carboxylic acid, which would decarboxylate to the N-H pyrazole.
Diamyd Medicals furthest developed project is the Glutamic Acid Decarboxylate (GAD)-based drug Diamyd[R] for autoimmune diabetes.