dedifferentiation

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Related to dedifferentiate: redifferentiation

dedifferentiation

[dē‚dif·ə‚ren·chē′ā·shən]
(biology)
Disintegration of a specialized habit or adaptation.
(cell and molecular biology)
Loss of recognizable specializations that define a differentiated cell.
(physiology)
Return of a specialized cell or structure to a more general or primitive condition.
References in periodicals archive ?
He and his colleagues have recently shown that some factor present in blood serum, newt or any other kind, can induce newt muscle cells to dedifferentiate.
Plastid differentiation is a synchronous process in each cell; that is, all the plastids of a cell differentiate and dedifferentiate simultaneously.
Reprogramming an adult cell to dedifferentiate it back into pluripotent stem cells is a key proposal (Option 4) in the 2005 President's Council on Bioethics white paper Alternative Sources of Human Pluripotent Stem Cells.
The predictive utility of tissue-derived cardiomyocyte pools is limited because they do not spontaneously beat, gradually dedifferentiate into fetal-like physiological states, and contain a high percentage of contaminating cell types, such as fibroblasts that can rapidly override the culture.
These potential demands actually provide a room for the smart phone industry to dedifferentiate in the future.