ROTTERDAM, Netherlands, June 27, 2012 /PRNewswire/ -- Data presented today from the Privigen Impact on Mobility and Autonomy (PRIMA) trial at the Peripheral Nerve Society Inflammatory Neuropathy Consortium Meeting in Rotterdam, Netherlands, suggests that treatment with Privigen[Immune Globulin Intravenous (Human), 10% Liquid], an intravenous immunoglobulin (IVIg), may lead to improvement in function in patients with chronic inflammatory demyelinating
Several reasons argue for a demyelinating
CNS disease of autoimmune aetiology in the present case.
While investigating the cortical changes in the biopsies, researchers were struck by the high frequency of cortical demyelinating
Additionally, a recent report presented a case of concomitant GD and clinically isolated demyelinating
disease in childhood linking thyroid and CNS dysfunction (12).
Diagnostic tables summarize the criteria for cerebrovascular diseases; dementias and behavioral disorders; demyelinating
disorders; epilepsy; genetic syndromes; headache; immune-based disorders; infectious disease; movement disorders; neuromuscular disorders; pain, fatigue, and trauma; and sleep disorders.
TNF blockade both prevents and abrogates demyelinating
disease in vitro and in animal studies.
Would it be possible to use fetal transplants to reverse demyelinating
disease in humans?
Acute disseminated encephalomyelitis (ADEM) is a rare idiopathic inflammatory demyelinating
disease of the central nervous system (CNS), which usually occurs following viral/bacterial infections or vaccinations (1).
He said: "So it is going to be interesting to see if prions play any role in demyelinating
diseases that stem from the brain.
Patients with rare, chronic inflammatory demyelinating
polyneuropathy (CIDP) depend on plasma donation
of Ottawa, Canada) assembles 21 chapters by scholars and practitioners from North America and Europe, who detail recent neurological research on multiple sclerosis and related demyelinating
diseases such as neuromyeletis optica and acute disseminated encephalomyelitis.
There have been no reports of demyelinating
disorders, heart failure, or end-organ toxicity.