dendritic


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dendritic

[den′drid·ik]
(science and technology)
Having a branching, treelike structure or pattern.
References in periodicals archive ?
FDCS is an intermediate grade sarcoma derived from follicular dendritic cells (FDC).
Immunohistochemical markers assist in arriving at the diagnosis of FDCS if the appropriate immunohistochemical markers specific for follicular dendritic cell differentiation/FDCS are applied.
Dendritic cells are antigen presenting cells that display the digested fragments of phagocytosed pathogens to other immune cells.
Part of the innate immune system that is the body's first line defense against infection, dendritic cells sense the presence of pathogens in the blood or other tissues, ingest infecting organisms and then display fragments of the invaders on their surface, which alerts and activates both killer and helper T cells (CD4 and CD8 cells), essentially teaching them to target the specific pathogen.
Thomas Ichim, PhD, Chief Scientific Officer of Regen, said, 'The dendritic cell is the most potent stimulator of the immune response, and controls whether T cells will be activated to kill tumors, or will be suppressed.
Under the new agreement, PCT will manufacture clinical supplies of ICT-140, a dendritic cell vaccine targeting seven ovarian cancer antigens, using process improvements PCT will develop that can be applied to the manufacture of all ImmunoCellular's current vaccine product candidates, ICT-107, ICT-121 and ICT-140.
First, that these mutations restore maturation of dendritic cells very effectively, and second, that a mutation in even one of these genetic domains makes the virus unable to suppress maturation.
To avoid infection of the white blood cells by the virus, scientists treated dendritic cells with heat- inactivated HIV and then delivered these cells back into the patients as a therapeutic vaccine.
A two-step staining method marked the CD1a positive dendritic cells and the CD83 positive dendritic cells, showing the infiltration by these cells of the pathological samples through a immunohistochemistry technique known as envision.
OBJECTIVE: We determined whether RyR activity is required for PCB effects on dendritic growth.
We suggest that retraction of dendritic arborizations and degeneration of the somatic configuration might lead to deficits in information processing and substance synthesis in senile cerebellar PCs.