deoxycholic acid


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deoxycholic acid

[dē¦äk·sə′käl·ik ′as·əd]
(biochemistry)
C24H40O4 One of the unconjugated bile acids; in bile it is largely conjugated with glycine or taurine.
References in periodicals archive ?
Reductions in Submental Fat Achieved With Deoxycholic Acid Injection (ATX-101) Are Maintained Over Time: Results from Long-Term, Follow-Up Studies"
The 4 major bile acids, lithocolic acid, cholic acid, deoxycholic acid and chenodeoxycholic acid (all supplied by Sigma Aldrich, SA) were selected for study.
In vitro data have shown that nebulized deoxycholic acid may impair surfactant activity (Griese, Schams, & Lohmeier, 1998).
The biliary proportion of hydrophobic deoxycholic acid also been suggested to be greater in patients with constipation than in healthy subjects.
Funabiki et al observed high concentrations of deoxycholic acid, lithocholic acid, and unconjugated bile acid in bile obtained from patients with an abnormal pancreaticobiliary junction (9).
Conversely, the bile-acid profile of human faeces contains 3[Alpha]-hydroxy-5[Beta]-cholanoic acid [TABULAR DATA FOR TABLE 1 OMITTED] (lithocholic acid; 7) and is dominated by deoxycholic acid.
The bile acids are crucial for digesting fat, but high levels of some bile acids - particularly one type called deoxycholic acid - have been linked toan increased risk of colon cancer.
These new solution certified reference materials (CRMs) consist of lithocholic acid, taurocholic acid and native and deuterium-labeled analogs of cholic acid, chenodeoxycholic acid, deoxycholic acid, and ursodeoxycholic acid.
The Kythera Biopharmaceutical drug named, Kybella, is identical to deoxycholic acid - a solution that aids the body to absorb fats that are naturally produced by the body, according to the FDA.