Dephosphorylation


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Dephosphorylation

 

the splitting-off of a phosphoric acid group from a molecule of a compound containing phosphorus. Some unstable organic phosphorus compounds can undergo spontaneous dephosphorylation, but in living organisms dephosphorylation proceeds primarily with the participation of enzymes. Dephosphorylation brought about by kinases (creatine kinase, glucokinase, and so on) leads to the transfer of the phosphoric acid group to other compounds. Dephosphorylation that is catalyzed by phosphorylases (phosphoamidases) results in the formation of free phosphoric acid. The differentiation among the various types of fermentative dephosphorylation is to some extent arbitrary.

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23],[24] Because PP2A-dependent tau dephosphorylation is compromised in AD, elevations in p-tau in AD brain may be due to reduced tau dephosphorylation.
The addition of etoposide induced the accumulation and dephosphorylation of Ulk1 in Atg5-deficient MEFs.
Dephosphorylation of bacterial CpG DNA and flagellin by IAP inhibits the induction of IL-8 proinflammatory cytokines, mediated by TLR recognition (Chen et al.
Antioxidant Effects of ACE and QCT Are Mediated by ERK1/2 Phosphorylation and p38MAPK Dephosphorylation.
Liver Panel Tests Used to identify Hy's Law Cases Liver Panel Test Function Alanine Enzyme for energy metabolism; involved in aminotransferase (ALT) gluconeogenesis and amino acid degradation Aspartate Enzyme for energy metabolism; involved in aminotransferase (AST) gluconeogenesis and amino acid degradation Bilirubin (total) Product of normal heme catalysis Alkaline phosphatase Enzyme for protein regulation; involved in (ALP) dephosphorylation Liver Panel Test Normal Range Hy's Law Range Alanine 10 to 40 IU/L [greater than or equal aminotransferase (ALT) to] 3x ULN Aspartate aminotransferase (AST) 10 to 34 IU/L [greater than or equal to] 3x ULN Bilirubin (total) 0.
Dephosphorylation of tyrosine phosphorylated synthetic peptides by rat liver phosphotyrosine protein phosphatase isoenzymes.
PSI]] and the surfactant concentration for a spontaneous dephosphorylation of bis-p-MPPE is presented in Fig.
Furthermore, the importance of Actinomycetes in dephosphorylation of soil organic compounds needs to be elucidated in further studies.
Within the smooth muscle of the gastrointestinal tract, they behave similarly by increasing the production of cyclic GMP and in turn, causing dephosphorylation of the myosin light chain and subsequent inhibition of smooth muscle contraction.
This mutation in the promoter region of PPP3CA may enhance its transcription, inducing higher NFAT dephosphorylation and translocation to the nucleus, thus resulting in an augmentation of the cytokines produced downstream.
NO activates the soluble guanylate cyclase, increases the synthesis of cGMP, activates protein kinase A, and leads to the cascades of effects in the smooth muscle, ending with the dephosphorylation of light myosin chains, and the removal of [Ca.
A decline in its insulin-mediated dephosphorylation to its inactive form.