(redirected from depolarizing)
Also found in: Dictionary, Thesaurus, Medical.


The removal or prevention of polarization in a substance (for example, through the use of a depolarizer in an electric cell) or of polarization arising from the field due to the charges induced on the surface of a dielectric when an external field is applied.
The resolution of polarized light in an optical depolarizer.



the decrease in the difference in potentials during the resting state (so-called resting potential) between the internal and external sides of the membrane of a living cell. In nerve cells and their processes, as well as in muscle fibers, depolarization is one of the most important components of the process of excitation. Stable depolarization may occur experimentally or in certain diseases as a result of direct damage to the membrane or disruption of metabolism.

References in periodicals archive ?
In general, the excitability of neuron can be characterized by the magnitude of the depolarizing current necessary to bring the membrane potential to the threshold leading to initiation of the action potential.
5] exposure in the form of iron-soot decreased neuronal excitability to depolarizing current injections (100-400 pA).
By activating these receptors, serotonin can enhance or inhibit neurotransmitter release at certain synapses and can produce slow hyperpolarizing or depolarizing synaptic responses at others.
This article explores the dilemmas associated with working with same-sex attracted (SSA) clients in religious conflict, the ethics of conversion therapy, social justice issues, and whether depolarizing the debate can or should be a goal.
Table The safety of selected drugs in patients susceptible to malignant hyperthermia Do not use (trigger agents) Cyclopropane Depolarizing muscle relaxants (e.
It seems only logical that a device capable of depolarizing skeletal muscle can also depolarize heart muscle and cause fibrillation under certain circumstances.
Characean action potentials can be induced by various stimuli, including suddenly lowered or raised temperature or pressure, UV irradiation, and odorants, as well as by a mechanical stimulation or a depolarizing current (Harvey, 1942a, 1942b; Hill, 1935; Kishimoto, 1968; Osterhaut & Hill, 1935; Staves & Wayne, 1993; Ueda et al.
Half of each group then viewed the normal sky, and half saw the sky through a depolarizing filter.
Precautions should also be taken in those patients who have had previous anaphylactic reactions to other neuromuscular blocking agents, since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported.
By blocking this co-transporter with bumetanide, a loop diuretic, the depolarizing action of GABA will be reversed resulting in reduced neuronal firing.
Attendees from multiple disciplines and ideological perspectives will discuss topics such as "how to fix the broken political system," "the psychology of partisanship" and "strategies for depolarizing the American electorate.
The NMBAs are divided into two types: depolarizing and non-depolarizing agents.