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depurination |
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depurination [dē‚pyu̇r·ə′nā·shən]
(biochemistry) Detachment of guanine from sugar in a deoxyribonucleic acid molecule. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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No references found | 85-93 DNA REPAIR PATHWAYS Errors in replication, extracellular influences such as UV light, radiation, and chemicals, and endogenous influences such as oxygen radicals routinely cause DNA damage, generally depurination, deamination, nonenzymatic methylation, and hydrolysis, sometimes with the attachment of a chemical group to DNA, the combination of which is termed an adduct. 2] can interact with DNA and, in turn, lead to depurination of DNA--a potential mutagenesis event (Cavalieri et al. This depurination of the SR loop results in irreversible inhibition of protein synthesis at the translation step by impairing both the elongation factor (EF) 1-dependent binding of aminoacyl-tRNA and the GTP-dependent binding of EF-2 to the affected ribosome (Gessner and Irvin, 1980). |
depurination |
Depulsion Depulsory DEPUR Depurant depurate depurate depurate depurated depurated depurates depurates depurating depurating depuration depuration depuration depurations depurations Depurative Depurative Depurative depuratives depuratives depurator depurator depurators depurators Depuratory Depure Depurgatory depurination DepuritionDeputable deputation deputation deputations deputations Deputator Deputatskii depute depute Député Député deputed deputed deputes deputes deputies deputies deputies Deputies Advisory Working Group Deputies Committee Deputies Committee of the National Security Council Deputies Law Enforcement Association deputing deputing deputise deputise deputised deputised deputises | |||||||
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