Pb stimulates delta-aminolevulinic acid synthetase (ALAS), through feedback derepression
, with a threshold in human leukocytes at a blood Pb of about 40 [micro]g/dl.
of tumor suppressor genes can lead to reversal of malignant cell behavior in vitro, and may be associated with a clinical effect in cancer patients.
McKenney DJ, Drury CF, Wang SW (2001) Effects of oxygen on denitrification, repression, and derepression
in soil columns.
3] CAUSE DEREPRESSION
OF TELOMERIC SILENCING IN SACCHAROMYCES CEREVISIAE
Longer anti-miRs to miR-122 were more effective than shorter anti-miRs as measured by target gene derepression
and impact on cholesterol levels (anti-miR-122 has been shown to reduce levels of LDL cholesterol).