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see skinskin,
the flexible tissue (integument) enclosing the body of vertebrate animals. In humans and other mammals, the skin operates a complex organ of numerous structures (sometimes called the integumentary system) serving vital protective and metabolic functions.
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(corium, cutis, true skin), the connective-tissue part of the skin in vertebrates and man, located beneath the epidermis.

The dermis is normally more or less loosely connected to the subjacent organs by loose subcutaneous connective tissue, which is often rich in fatty deposits. The dermis consists of two layers. The surface (papillary, spongy, subepithelial) layer functions mainly to nourish the epidermis and its derivatives (glands, feathers, hairs); it is rich in blood vessels, has a relatively loose structure, and, in some animals, forms papillae that project into the epidermis. The layer beneath it (reticular, compact) constitutes most of the dermis. It consists of solid connective tissue and has mainly a supportive function.


The deep layer of the skin, a dense connective tissue richly supplied with blood vessels, nerves, and sensory organs. Also known as corium; cutis.
References in periodicals archive ?
The tumor stage is often referred to as the non-epidermotropic stage because the papillary dermis and overlying epidermis are typically spared.
But many of the blood vessels in Mike's dermis have been destroyed--and with them, his ability to keep cool and warm.
Natural skin consists of two layers of cells: the flat epidermis, or upper layer, and the dermis, which lies underneath (see diagram, right).
Below the epidermis lies the dermis, a thicker skin-cell layer made of collagen, a tightly woven web of stringy protein fibers.
Produced from an African plant, tiger nut, Papilactyl D reinforces the structure of the papillary dermis involved in the majority of the cutaneous tissue's elastic properties, according to Silab.
Daniel Bucks, Dow's Director of Skin Biology and Drug Delivery, "Utilizing our Bronaugh Flow-Through Diffusion Cell Systems and two model compounds, we were able to evaluate the effect of human skin with an intact stratum corneum as well as isolated human dermis, receptor phase compositions and receptor fluid flow rate on skin penetration.
If a tattooist presses the gun against the skin, the needles can easily pierce fat or muscle beneath the dermis.
Echogenicity of the dermis was recorded and dermis density determined in two bands (superficial and low dermis).
The latest in the line up of outstanding choices CUTERA has to offer, Titan utilizes a safe infrared light source with a unique wavelength filtering design to uniformly heat the dermis.
Although the epidermis and papillary dermis are generally Unaffected, deep in the dermis are thick, tightly packed collagen fibers randomly oriented in irregular sheets (figure 1).
In most cases, cutaneous involvement is the result of a direct extension of extranodal carcinoma into the dermis and the dermal lymphatics.
Any drug in the patch travels through the next layers of skin, the epidermis and dermis, which contain blood vessels that absorb and disperse medication to the bloodstream.