perfringens toxins by dermonecrotic
test in albino guinea pigs:
Sea wasp (Chironex fleckeri) venom: lethal, haemolytic and dermonecrotic
The venom is neurotoxic, hemolytic, vasoconstrictive, and dermonecrotic
The fraction has the lethal effect on mice of whole venom, is dermonecrotic
to rabbits13 and has sphingomyelinase D activity16.
perfringens strains were then typed for their toxigenicity and typing by the mice neutralization test and dermonecrotic
test in guinea pigs (Murray et al.
1994), demonstrating the bacteria's dermonecrotic
ability and, if not treated or prevented, it can cause 80% mortality in larvicultures.
After that, an explosion of reports spread the word about the newly implicated Loxosceles spiders as dermonecrotic
Some investigators propose that dermonecrotic
properties are associated with a hydrophobic fraction.
Identification of staphylococcal Panton-Valentine leukocidin as a potent dermonecrotic
and lethal components of Loxosceles gaucho spider venom.
CNF1, CNF2, and the dermonecrotic
toxins from Bordetella species form a unique subset in this family, since these toxins have the capacity to activate Rho (Figure 1 C) (29-32).
Catalase_test ; Gelatin liquefaction test; indole test;nitrate reduction test ;Sugar_fermentation_test; hydrogen Sulphide production test (Oxoid) and litmus milk_medium : Nagler's test by half antitoxin plate : Typing of Clostridium perfringens toxins dermonecrotic
test in albino guinea pigs Toxin antitoxin neutralization test : Determination of the MLD of the prepared toxin : Antibiogram sensitivity test (Oxiod): Pathological, gross and histopathological examination