desmoplasia


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desmoplasia

[‚dez·mə′plā·zhə]
(medicine)
The formation and proliferation of connective tissue, frequently in the growth of tumors.
The formation of adhesions.
References in periodicals archive ?
Histopathologically, hybrid ameloblastomas show areas of extensive stromal collagenization or desmoplasia surrounding compressed islands of the odontogenic epithelium.
Barsky, "Human breast carcinoma desmoplasia is PDGF initiated," Oncogene, vol.
15,16 It morphologically resembles ductal carcinoma of the breast frequently showing comedo type necrosis, an infiltrative growth pattern with marked stromal desmoplasia, vascular and perineural invasion and regional lymph node involvement.
On postmortem examination, histologic sections of the cranium at the level of the mass showed marked desmoplasia around the neoplastic cells and extensive reactive bone remodeling with branching trabeculae of bone extending throughout the neoplasm in former areas of normal skull (Fig 4).
Patients were considered for surgery alone if they had favorable T1 to T3 tumors resected with clear margins and without adverse pathologic prognostic factors, including angiolymphatic invasion, desmoplasia, or perineural invasion.
In some invasive tumors, revascularization occurrs adjacent to a region of desmoplasia rich in HA.
La desmoplasia es aumentada en carcinomas mamarios probablemente como un resultado de la secrecion de factores conocidos como moduladores de la actividad biosintetica (entre estos factores se citan TGFb, TGFa, PDGF, FGF) en las celulas mesenquimales tumorales (25).
Histologically, the desmoplasic ameloblastoma is characterized by a stroma with intense desmoplasia, densely collagenized, comprising little odontogenic epithelium islands and cords of various sizes (Iida et al.
The tumor is so named because of prominent stromal desmoplasia (Figure 13, F).
2) un encapsulated subvariant included infiltraive and diffuse variant, infiltrative if there was absent or incomplete encapsulation with invasive tongues of tumor infiltrating non neoplastic thyroid parenchyma, almost always with prominent fibrosis; diffuse if 1 lobe or an entire thyroid was involved by a non-encapsulated, diffuse, or multinodular tumor without desmoplasia and with pushing borders or absence of a clear cut delineation between the tumor and the adjacent parenchyma.