Clinical suspicion for Pott's disease should be high for any patient who presents with a destructive lesion
of the spine.
Antineutrophil cytoplasmic antibodies reacting with human neutrophil elastase as a diagnostic marker for cocaine-induced midline destructive lesions
but not autoimmune vasculitis.
Complications consisted of foot drop in two patients, both of which had large destructive lesions
involving the sacrum.
One indication for MRI at midgestation emerges when there are borderline findings on ultrasound, such as those that might be seen with progressive or destructive lesions
that won't be fully realized until late in pregnancy.
As an alternative to destructive lesions
, much interest is currently directed to the use of stereotactically implanted permanent quadripolar electrodes and impulse generators for deep brain stimulation (DBS).
Multiple myeloma usually arises in the bone marrow and is characterized by interference with the production of blood cells, destructive lesions
of bone that can cause debilitating fractures, and excessive production of antibody molecules.
Other diagnostic considerations for destructive lesions
in the mastoid include endolymphatic sac tumors and contiguous lesions from nasopharyngeal carcinoma and paragangliomas.
Cholesteatomas are non-neoplastic but destructive lesions
containing layers of keratin in a cavity lined by squamous epithelium.
Multiple myeloma usually arises in the bone marrow and is characterized by interference with production of blood cells, destructive lesions
of bone that can cause debilitating fractures, and excessive production of specific antibody molecules.