For example, many students (according to some studies over 5%) and their professors (according to some studies up to 20%) in the United States use drugs such as modafinil (brand name for example Provigil), metylphenidate (brand name for example Ritalin) and dextroamphetamine
(brand name for example Adderall), to increase their recall, attention span, problem-solving ability, and ability to focus on cognitive tasks.
In addition to opiates, stimulants such as methylphenidate (Ritalin) and dextroamphetamine
(Dexedrine), used to treat attention deficit hyperactivity disorder, are popular with students needing to pull an "all-nighter" and executives needing that little "something" to outperform peers.
This experiment will determine if mice treated with dextroamphetamine
during adolescence will have increased locomotor activity in adulthood when challenged with a sub-acute dose of METH (0.
in Fort Lauderdale, Florida ("Watson") advising of the filing of an Abbreviated New Drug Application ("ANDA") for a generic version of all approved strengths of Shire's ADDERALL XR (mixed salts of a single-entity amphetamine product) dextroamphetamine
saccharate, amphetamine aspartate monohydrate, amphetamine sulphate capsules, CII.
Stimulants are the most frequently prescribed medications used to treat ADD/ADHD and include methylphenidate (Concerts[R], Daytrana[TM], Metadate[R] CD, Metadate[R] ER, Methylin[R], Methylin[R] ER, Ritalin[R], Ritalin LA[R], Ritalin-SR[R]); dextroamphetamine
(Dexedrine[R], DextroStat[R], Liquadd[TM]; dextroamphetamine
and amphetamine (Adderall[R], Adderall XR[R]); and lisdexamfetamine (Vyvanse[TM]).
Coanalgesics: antihistimines, dextroamphetamine
, ketamine, skeletal muscle relaxants, topical agents, tetrodotoxin
Actavis had sued the FDA to overturn the exclusivity because Vyvanse is a metabolically converted drug and its active ingredient, dextroamphetamine
, is the same as the older drug Adderall.
Stefanatos found that dextroamphetamine
(D-AMPH), a drug commonly used to treat ADHD can help process speech in the brain.
Studies show that patients treated with dextroamphetamine
and morphine sulfate experience 50% to 100% more pain relief than those with placebo and morphine (17).
3) More recently, the military's use of dextroamphetamine
to sustain the performance of sleep-deprived pilots created concern after two pilots blamed a friendly-fire incident in 2002 on their use of this medication.
On the other hand, lisdexamfetamine (Vyvanse), which is indicated for attention-deficit/hyperactivity disorder, is a prodrug of dextroamphetamine
, a drug known to cause human developmental toxicity.
The success of CNS stimulants in promoting wakefulness has led to both dextroamphetamine
and Modafinil becoming FDA-approved for alleviating symptoms of the excessive daytime sleepiness associated with narcolepsy.