dextrorotatory enantiomer

dextrorotatory enantiomer

[‚dek·strō′rōd·ə‚tȯr·ē ə¦nan·tē¦ō·mər]
(organic chemistry)
An optically active substance that rotates the plane of plane-polarized light clockwise. Symbolized d. Also known as dextro.
Mentioned in ?
References in periodicals archive ?
The unexpected properties of Plavix[R], the dextrorotatory enantiomer of clopidogrel, ultimately rendered the compound nonobvious over its racemate.
154) Once separated, it was determined that the dextrorotatory enantiomer imparted all of the beneficial antiplatelet activity, while the levorotatory enantiomer imparted all of the neurotoxicity of the racemate.
161) Therefore, the unpredictable properties of the resulting enantiomers, coupled with the uncertainty of the separation, ultimately rendered the dextrorotatory enantiomer of clopidogrel nonobvious.
Forest, the owner of a patent covering the racemic antidepressant citalopram, was granted a patent on the dextrorotatory enantiomer of citalopram.
The district court, with the Federal Circuit affirming, held that the difficulty of the separation and the unexpected properties of the dextrorotatory enantiomer rendered the enantiomer nonobvious in spite of the racemate.
Together with a licensee PAZ has developed dexibuprofen, the dextrorotatory enantiomer of ibuprofen as first product of this kind and launched it in 26 countries as an analgetic and antiinflammatory drug.