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diabetes insipidus

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diabetes insipidus

Endocrine disorder causing extreme thirst and excessive production of very dilute urine, apparently due to lack of antidiuretic hormone (vasopressin, which regulates the kidney's water conservation and urine production) or failure of the kidney tubules to respond to it. Injections of synthetic vasopressin are effective if the hormone is lacking but not if the response is absent. Disorders of the hypothalamus are one cause of diabetes insipidus.


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When it appears that the patient has diabetes insipidus stemming from pituitary involvement, a water-deprivation test may be indicated.
A case of transient diabetes insipidus associated with poisoning by a herbicide containing glufosinate.
Other products include ACTHREL(R) (corticorelin ovine triflutate for injection) for the differential diagnosis of Cushing's syndrome and generic desmopressin acetate in injectable and rhinal tube forms for the treatment of diabetes insipidus and primary nocturnal enuresis.
 
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