ddI

(redirected from dideoxyinosine)
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ddI

and

ddC:

see AZTAZT
or zidovudine
, drug used to treat patients infected with the human immunodeficiency virus (HIV), which causes AIDS; also called azidothymidine. Originally developed in 1964 as an anticancer drug, AZT was never approved for that purpose.
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References in periodicals archive ?
pointed out that the recent approval of dideoxyinosine (DDI) -- the second drug that has been found to be effective against AIDS -- was made possible by the application of several innovative concepts recommended by the working group.
8%) without inducing drug resistance, significantly increased CD4+ T cells by up to 135 cells/mm3in the dideoxyinosine 200 mg/hydroxycarbamide 900 mg cohort (doses lower than traditionally investigated), while also rapidly and significantly reducing markers of excessive immune activation.
Agent Effective Ineffective Interferon Interferon-[alpha] Interferon-[gamma] Antiviral Acyclovir Dideoxyinosine Azudothymidine Foscarnet Immunomodulatory Prednisone Interleukin-2 Thymosin Levamisole Agent Toxic Under evaluation Interferon Interferon [beta] Antiviral Fialuridine Ribavirin Adenine Lamivudine Arabinoside Immunomodulatory Adoptive immune transfer Modified from Lok ASF.