diethylcarbamazine


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diethylcarbamazine

[‚dī‚eth·əl‚kär′bam·ə‚zēn]
(organic chemistry)
C16H29O8N3 White, water-soluble, hygroscopic crystals, melting at 136°C; used as an anthelminthic.
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Test samples and reference drug diethylcarbamazine (DEC) were dissolved in DMSO or sterile distilled water, respectively.
Impact of two annual single-dose mass drug administrations with diethylcarbamazine alone or in combination with albendazole on Wuchereria bancrofti microfilaraemia and antigenaemia in south Indiai Trans R Soc Trop Med Hyg 98: 174, 2004.
Effect of yearly mass drug administration with diethylcarbamazine and albendazole on bancroftian filariasis in Egypt: a comprehensive assessment.
Treatment of bancroftian filariasis in Recife, Brazil: A two-year comparative study of the efficacy of single treatment with ivermectin or diethylcarbamazine.
Background & objectives: Albendazole, a commonly used anthelminthic drug that targets the polymerization of [alpha]- and [beta]-tubulin dimer is currently co-administered with the antifilarial drug, diethylcarbamazine citrate (DEC) in the ongoing Global Programme for Elimination of Lymphatic Filariasis (GPELF).
The authors conclude this can become an inexpensive filaricide of natural origin more effective than diethylcarbamazine, a reference pharmaceutical.
Both were treated with diethylcarbamazine, the drug of choice for W.
While Albendazole is donated by GSK, diethylcarbamazine (DEC) needs to be purchased for the treatment of lymphatic filariasis in countries without river blindness.
In support of the World Health Organization (WHO)'s program to eliminate lymphatic filariasis by 2020, Eisai is supplying diethylcarbamazine (DEC) free of charge to WHO.
Headquarters: Tokyo, President & CEO: Haruo Naito, "Eisai") announced today that it has begun the free supply of diethylcarbamazine citrate (DEC) 100 mg tablets produced at its Vizag Plant in India to the World Health Organization (WHO) in line with its commitment to help WHO in its global effort to eliminate lymphatic filariasis in targeted developing and emerging countries.
Coverage and compliance to diethylcarbamazine in relation to Filaria Prevention Assistants in rural Puducherry, India.