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digitonin

   Also found in: Medical, Wikipedia 0.03 sec.
digitonin [‚dij·ə′tō·nən]
(pharmacology)
C41H64O13A glycoside derived from the purple foxglove plant (Digitalis purpurea); a white powder melting at 255-256°C; used as a medicine for cardiac conditions.


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Germinally transgenic tadpoles were produced by restriction enzyme-mediated integration nuclear transplantation according to Kroll and Amaya (1996), with the following modifications: sperm was purified by centrifugation on a two-layer discontinuous Percoll (Sigma) gradient before the permeabilization step, which was performed with digitonin (Sigma) instead of lysolecithin.
The results were expressed as the percentage of ATP released relative to the total ATP present in cells lysed by means of digitonin (50 [micro]M) (16).
 
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