digitoxin


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digitoxin:

see digitalisdigitalis
, any of several chemically similar drugs used primarily to increase the force and rate of heart contractions, especially in damaged heart muscle. The effects of the drug were known as early as 1500 B.C.
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digitoxin

[‚dij·ə′täk·sən]
(organic chemistry)
C41H64O13 A poisonous steroid glycoside found as the most active principle of digitalis, from the foxglove leaf.
References in periodicals archive ?
Simultaneous determination of digoxin and digitoxin by micellar electrokinetic chromatography and application to drug formulations.
Cytotoxicity of digitoxin and related cardiac glycosides in human tumor cells.
Clinical applications of pharmacokinetics and control theory: Planning, monitoring, and adjusting dosage regimens of aminoglycosides, lidocaine, digitoxin, and digoxin.
Think of foxglove, a toxic plant, source of digitoxin and a powerful heart drug.
Foxgloves Grown for heart drugs digitoxin and digoxin.
By the early 20th century, the active ingredients, digitoxin and digoxin were isolated, making standardized preparations readily available.
Verleichende studein uber wirkungen eines Crataegus-extraktes, ven digitoxin, digoxin, und gstrophanthin am isolierten warmbluterherzen.
Medications What They Do Generic name (sample brand names) Cardiovascular Medications Anti-Arrhythmia Medications: Improve the strength and digoxin (Lonoxicaps, Lanoxin) efficiency of the heart by digitoxin (Crystodigin) regulating heart rate.
Michael Balick and Paul Alan Cox list fifty drugs that were developed through leads provided by traditional medicinal knowledge or ethnobotanical leads, including aspirin, digitoxin, and digoxin for cardiac treatment, quinine for malaria, and vinblastine and vincristine for the treatment of particular kinds of cancer .
Digitalis, derived from the foxglove plant, is also known as digoxin and digitoxin.
For example, digitoxin was added in 1947, while digitalis leaf powder was deleted in 1975.
Digoxin and digitoxin are the two glycosides mainly used, the former due to its more rapid elimination in case of intoxication [5].