digoxin


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digoxin:

see digitalisdigitalis
, any of several chemically similar drugs used primarily to increase the force and rate of heart contractions, especially in damaged heart muscle. The effects of the drug were known as early as 1500 B.C.
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digoxin

[dī′gäk·sən]
(organic chemistry)
C41H64O14 A crystalline steroid obtained from a foxglove leaf (Digitalis lanata); similar to digitalis in pharmacological effects.
References in periodicals archive ?
5A illustrates the absorptive (AP [right arrow] BL) and secretory (BL [right arrow] AP) transport of digoxin on LLC-PK1 cells (lacking P-gp), in the absence and presence of 10 [micro]M verapamil, SLE (0.
The archaeal beta hydroxyl steroid dehydrogenase activity indicating digoxin synthesis was increased [8].
Exhumed remains of another infant showed digoxin toxicity when Nelles had been off work for several days.
During the study, the researchers treated prostate cancer cells grown at normal and low-oxygen levels with digoxin for three days, and counted the number of cells each day.
Digoxin and omeprazole have not been reported to have significant drug-drug interactions, although they are both minor substrates of the enzyme CYP3A4.
Aliquots of drug-free serum pools were supplemented with ginseng and apparent digoxin concentrations were measured using enzyme-linked chemiluminescent immunosorbent digoxin assay, turbidimetric assay, and fluorescence polarization immunoassay digoxin assays.
Effect of Chinese medicines Chan Su and Danshen on EMIT 2000 and Randox digoxin immunoassays: wide variation in digoxin-like immunoreactivity and magnitude of interference in digoxin measurement by different brands of the same product.
An example of the latter is Digibind, which consists of Fabfragments of digoxin antibody, administered to neutralize digitalis toxicity.
The court considers it beyond any reasonable doubt that (De Berk) gave Amber Zuidewijk digoxin and she died because of it.
Because hawthorn interferes with serum digoxin measurements using the Digoxin III assay, the possibility of eliminating this interference was considered and subsequently studied by monitoring free digoxin concentrations.
two nurses must be present when Digoxin is administered to a patient.
Plant-derived cardiac glycosides such as digoxin are used for the treatment of congestive heart failure and other cardiac disorders (1).