cacodylic acid

(redirected from dimethylarsinic acid)
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Related to dimethylarsinic acid: Cacodylic acid

cacodylic acid

[¦kak·ə¦dil·ik ′as·əd]
(organic chemistry)
(CH3)2 AsOOH Colorless crystals that melt at 200°C; soluble in alcohol and water; used as a herbicide.
References in periodicals archive ?
DNA-strand breaks induced by dimethylarsinic acid, a metabolite of inorganic arsenics, are strongly enhanced by superoxide anion radicals.
Identification and quantification by LC-MS and LC-ICP-MS of arsenic species in urine of rats chronically exposed to dimethylarsinic acid (DMAA).
Minor amounts of monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), and methylated arsenic (III) species can also be present in natural waters.
The urinary excretion of arsenic metabolites after a single oral administration of dimethylarsinic acid to rats.
Speciation measurements by HPLC-HGAAS of dimethylarsinic acid and arsenobetaine in three candidate lyophilized urine reference materials.
Most of the inorganic arsenic, As(III) and As(V), is metabolized to dimethylarsinic acid (DMA) [4] and monomethylarsonic acid (MMA) before excretion into the urine.
We examined total urinary arsenic (excluding arsenobetaine and arsenocholine) and dimethylarsinic acid (DMA) concentrations overall and by age group: 6-11 years and 12-17 years.
The 50% lethal doses for oral administration to mice are as follows: 3 mg/kg for arsine; 14 mg/kg for arsenite [As(Ill)]; 20 mg/kg for arsenate [As(V)]; 700-1800 mg/kg for monomethylarsonic acid (MMA), (4) 700-2600 mg/kg for dimethylarsinic acid (DMA); and >10 000 mg/kg for arsenobetaine and arsenocholine (1).
Metabolic status was based on urinary concentrations of methylarsonic acid (MMA) and dimethylarsinic acid (DMA), and multivariable logistic regression was used to estimate associations.
Arsenite [As(III)], arsenate [As(V)], monomethylarsonic acid (MMAA), and dimethylarsinic acid (DMAA) are widely present in the natural environment [25-29].
One finding was that uCr was the strongest predictor of As methylation; participants with higher uCr concentrations had a higher percentage of total urinary As as dimethylarsinic acid (DMA) compared to those with lower uCr.
As species calibrators of monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), and arsenobetaine (AsB) were provided by the Commission of the European Union, DGXII, Measurements and Testing Programme.