dioxolane


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dioxolane

[dī′äk·sə‚lān]
(organic chemistry)
C3H6O2 A cyclic acetal that is a liquid; used as a solvent and extractant.
References in periodicals archive ?
Their topics include the chemical synthesis of acyclic nucleosides, mononucleotide pro-drug synthetic strategies, synthesizing conformally constrained nucleoside analogues, stereoselective methods in synthesizing bioactive oxathiolate and dioxolane nucleosides, and synthetic studies on antifungal peptidyl nucleoside antibiotics.
My last remuneration for a drug study was more than 45 years ago, when I tested a combination of dioxolane and reserpine.
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase.
Troxacitabine was discovered by BioChem Pharma and is the first dioxolane nucleoside analogue anticancer agent.
Our new "DOI" dioxolane based (meth)acrylates offer low skin irritation and unique properties.
Laval, Canada) has patented a process for stereoselectively producing a dioxolane nucleoside analogue from an anomeric mixture of .
Dimers of gA can be obtained by introduction of a dioxolane ring between N-formylated termini of two gA molecules.
Troxatyl(TM) (troxacitabine) is the first dioxolane nucleoside analog to be investigated as an anticancer agent in clinical trials.
A second drug in this class is amdoxovir (also called diaminopurine dioxolane or DAPD).
Seebach discussed the catalytic use of similar complexes derived from tetraaryl dioxolane dimethanols (TADDOLs) and tetraisopropoxy titanium to mediate asymmetric addition of organozinc compounds to compounds such as saturated and unsaturates aldehydes.
DAPD is a novel dioxolane purine nucleoside reverse transcriptase inhibitor (NRTI) that is in Phase I/II trials for the treatment of HIV.
DAPD is a novel dioxolane purine nucleoside reverse transcriptase inhibitor (NRTI) that is rapidly converted in humans into its active metabolite, DXG.