dioxygenase


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dioxygenase

[dī′äk·sə·jə‚nās]
(biochemistry)
Any of a group of enzymes which catalyze the insertion of both atoms of an oxygen molecule into an organic substrate according to the generalized formula AH2+ O2→A(OH)2.
References in periodicals archive ?
According to a new study published in the Nature Journal Scientific Reports, high levels of this enzyme, indoleamine 2,3 dioxygenase (IDO) at diagnosis also identifies those who might benefit most by taking an IDO inhibitor along with their standard therapy.
They also reinforce that the similarity can be explained by hegemony analyzes, in which L-DOPA dioxygenase, enzyme that leads to the formation of betalamic acid precursor of many betalains, bears similarity to enzymes of the route of anthocyanin biosynthesis.
The TET enzyme contains a catalytic C-terminal Cys-rich (CD domain) and double-stranded beta helix region domains that show dioxygenase activity [19].
Among the 2-oxoglutaric acid-dependent dioxygenase genes involved in the pathway, flavanone 3-hydroxylase gene (F3H) and anthocyanidin synthase gene (ANS) had the highest levels of expression, suggesting that the loss of red color might be the reason of the synergistic inhibitory effect of these enzymes especially F3H and ANS in response to Pro-Ca.
Keratin degradation by dermatophytes relies on cysteine dioxygenase and a sulfite efflux pump.
Such an excessive indoleamine 2, 3- dioxygenase stimulation can lead to a tryptophan decrease in serum, which is accompanied by a significant reduction of 5-HT synthesis.
Characterization of the 9-cisepoxycarotenoid dioxygenase gene family and the regulation of abscisic acid biosynthesis in avocado.
Ciorba, "Indoleamine 2,3 dioxygenase in intestinal disease," Current Opinion in Gastroenterology, vol.
Aside from its broad antioxidant properties, it has also recently been reported to participate in the hydroxylation of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) in DNA, catalyzed by ten-eleven translocation (TET) methylcytosine dioxygenase.
More studies have shown that the immunosuppressive effects were associated with two mechanisms; first, soluble factors such as indoleamine 2,3 dioxygenase (IDO), prostaglandin E2 (PG E2), transforming growth factor beta (TGF-[beta]) and second, cell-cell contact (20-23).
It is caused by the lack of an enzyme called homogentisic dioxygenase which means that patients cannot fully break down a toxic acid called homogentisic acid (HGA).