dioxygenase


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dioxygenase

[dī′äk·sə·jə‚nās]
(biochemistry)
Any of a group of enzymes which catalyze the insertion of both atoms of an oxygen molecule into an organic substrate according to the generalized formula AH2+ O2→A(OH)2.
References in periodicals archive ?
In the upper pathway, hydroxylation of an aromatic ring to a cis-dihydrodiol is catalyzed by dioxygenase, a multicomponent enzyme consisting of reductase, ferrodoxin, and large and small iron-sulfur proteins (ISP).
b) C, acetaminophen; D, ANIT; E, phenobarbital; F, Wy-14, 643; HPPD, 4-hydroxyphenylpyruvate dioxygenase.
beta]-Hydroxylation of trimethyllysine by an [alpha]-ketoglutarate-dependent mitochondrial dioxygenase.
Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase.
Determination of serum kynurenine and hepatic tryptophan dioxygenase activity by high-performance liquid chromatography.
NF-KB activation contributes to indoleamine dioxygenase transcriptional synergy induced by IFN-y and tumor necrosis factor-a.
Low-abundance clones containing TET2 [5] (tet methylcytosine dioxygenase 2) mutations in chronic myelomonocytic leukemia patients confer no prognostic value (6).
Taurine/alpha-ketoglutarate dioxygenase, known as TauD, is a bacterial enzyme that is important in metabolism.
However, as the activities of cysteine dioxygenase (CD) and cysteine sulfinic acid decarboxylase (CSAD) which are enzymes involving in taurine synthesis are too low to trigger taurine biosynthesis in the human body (Rigo and Senterre, 1977; Sturman and Hayes, 1980), taurine should be supplied from outside.
Frederic's presentation was entitled 'The Inactivation of 2,3-dihydroxybiphenyl dioxygenase, a Key Enzyme of PCB Catabolism'.
Cyclooxygenase is the key enzyme in prostaglandin biosynthesis and acts both as a dioxygenase and as a peroxidase.