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dioxygenase

   Also found in: Medical 0.01 sec.
dioxygenase [dī′äk·sə·jə‚nās]
(biochemistry)
Any of a group of enzymes which catalyze the insertion of both atoms of an oxygen molecule into an organic substrate according to the generalized formula AH2+ O2→A(OH)2.


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4,5) It has also been suggested that cysteine dioxygenase is involved in this biotransformation reaction, but to date no experimental evidence to support this hypothesis has been published.
Details of the research will be published in a February 15 online version of Proceedings of the National Academy of Sciences of the United States of America (PNAS), under the title of "Crystal structure of human indoleamine 2,3-dioxygenase: Catalytic mechanism of O2 incorporation by a heme-containing dioxygenase.
Mutations were noted in uridine kinase (gi29654198) in ST18, ST22, ST23, ST25, and ST29; in ompA-like transmembrane domain protein (gi29654257), in ST20; in rhodanese-like domain protein (gi29654263) in ST20 (the protein was longer by 2 amino acids); in dioxygenase (gi29654325) in ST21 and ST22; in hypothetical protein (gi29732244), in ST17.
 
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