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Dilantin
(redirected from diphenylhydantoin)

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Dilantin (dī`lăntĭn), trade name for diphenylhydantoin, an anticonvulsant drug. The first nonsedative antiepileptic agent, it is still widely used to control the grand mal type of epilepsy epilepsy, a chronic disorder of cerebral function characterized by periodic convulsive seizures. There are many conditions that have epileptic seizures. Sudden discharge of excess electrical activity, which can be either generalized (involving many areas of cells in
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. It is also useful against types of psychomotor epilepsy, i.e., epilepsy involving bizarre patterns of movement. In some cases Dilantin, in combination with phenobarbital, a barbiturate barbiturate (bärbĭch`ərāt'), any one of a group of drugs that act as depressants on the central nervous system .
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, is more effective than either drug used alone.


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Comparison of the effects of propylthiouracil, amiodarone, diphenylhydantoin, phenobarbitol, and 3-methylcholanthrene on hepatic and renal [T.
The neurologic hazards of diphenylhydantoin childhood, J Pediatr 1968;73:676-84.
Studies comparing tumors observed at the same sites after early postnatal and chronic adult exposures in a single protocol were available for six chemicals that do not act through a mutagenic mode of action [amitrole, dichlorodiphenyltrichloroethane (DDT), dieldrin, ethylene thiourea (ETU), diphenylhydantoin (DPH), polybrominated biphenyls (PBB); Table 5].
 
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