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diphtheria antitoxin |
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diphtheria antitoxin [dif‚thir·ē·ə ‚ant·i′täk·sən] (immunology) An antibody produced in animals or in humans after contact with diphtheria toxin or toxoid. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Joseph Kinyoun, the founder of the Hygienic Laboratory--predecessor of the National Institutes of Health--learned the procedure for preparing diphtheria antitoxin at the Pasteur Institute in Paris. Cinchona (and then purified quinine) won ready acceptance, as did the diphtheria antitoxin developed by Emile Roux in the 1890s, because, Ackerman argues, they demonstrably worked; there was even some popular demand in the later decades for disinfection services, in part, she suggests, because the treatment of infected bedding killed vermin. In a population-based study in the Netherlands, diphtheria antitoxin antibodies were measured with a toxin-binding inhibition assay in 9,134 sera from the general population and religious communities refusing vaccination. |
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