dipolar aprotic solvent

dipolar aprotic solvent

[dī‚pō·lər ā‚präd·ik ′säl·vənt]
(organic chemistry)
A solvent with characteristically high polarity and low reactivity, that is, a solvent having a sizable permanent dipole moment that cannot donate labile hydrogen atoms to form strong hydrogen bonds; examples include acetonitrile, dimethyl sulfoxides, and hexamethylphosphoramide.
References in periodicals archive ?
The present study is a part of our systematic investigation [4, 5] of thermodynamic properties of synthesized biologically active dihydro pyrimidines in dipolar aprotic solvents.
However, in dipolar aprotic solvents, which have a high dielectric constant and no hydrogen bond donor ability, for example acetonitrile, ion--neutral association processes are very important: the poorly solvated anions are stabilized by hydrogen bonding with neutral acids.
Acid-Base Dissociation Constants in Dipolar Aprotic Solvents.