displacement chromatography


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displacement chromatography

[dis′plās·mənt ‚krō·mə′täg·rə·fē]
(analytical chemistry)
Variation of column-development or elution chromatography in which the solvent is sorbed more strongly than the sample components; the freed sample migrates down the column, pushed by the solvent.
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By using displacement chromatography in the first dimension, one can better analyze and prove product purity through greater sensitivity and precision in identification of trace components.
In the first dimension one uses displacement chromatography to concentrate low abundance materials in discrete transition zones within the displacement train.
The results of 2-D HPLC with displacement chromatography are impressive and this new e-Learning course illustrates the power of integrating this method into critical analytical analysis," remarks Rosemary Hoffman, Director, Biotechnology Solutions Group at SACHEM.
AUSTIN, Texas -- In response to customer demand, SACHEM is now offering a new services program to help displacement chromatography users to quickly apply the technology in their laboratory and plant.
SACHEM's displacement chromatography services include:
Online displacement chromatography course - interactive, customized, simulation-based program that enables users to gain a deeper understanding of displacement chromatography.
Onsite seminars - SACHEM's Displacement Chromatography Seminar details concepts of displacement chromatography and resulting outcomes using SACHEM displacers, with time allotted for discussion regarding the customer's specific separation challenges.
Purification services - customized, contract purification services for customers desiring SACHEM's expertise in executing efficient, reliable, accurate displacement chromatography.
By illustrating critical choices in setting up a successful displacement chromatography experiment, users gain a basic understanding of the technology, and then can apply and optimize displacement chromatography more efficiently in the lab or plant," stated Rosemary Hoffman, Director of SACHEM's Biotechnology Solutions Group.