A sampling of individual paper topics includes displacement chromatography
of biomacromolecules, principles of membrane separation processes, removal and analysis of contaminants and impurities, and the manufacture of gene therapy products and viral vaccines.
In displacement chromatography, a sample is loaded on the ion-exchange media, followed by a solution of a molecule that binds to the media more tightly than any of the sample components.
In sample-self displacement chromatography of phosphorothioate oligonucleotides, the full-length, fully thioated oligonucleotide component in the sample that has the highest charge, hence the highest affinity for the stationary phase (the chromatography media), acts as the displacer.
The use of displacement chromatography to alter retention and enantioselectivity on a human serum albumin-based HPLC chiral stationary phase: a mini-review.
Comparison of drug binding interactions on human, rat and rabbit serum albumin using high-performance displacement chromatography.
AUSTIN, Texas -- SACHEM announced today the launch of a new displacement chromatography
SACHEM Responds to Customer Demand by Offering Onsite Expertise to Support Scientists in Evaluating and Applying Displacement Chromatography
The course includes a series of simulations designed to foster a deeper customer understanding of how SACHEM's ultra pure chemicals are used in the displacement chromatography