dissociation constant


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dissociation constant

[də‚sō·sē′ā·shən ‚kän·stənt]
(physical chemistry)
A constant whose numerical value depends on the equilibrium between the undissociated and dissociated forms of a molecule; a higher value indicates greater dissociation.
References in periodicals archive ?
These plots reveal if the ligand has the ability to form a slowly dissociating step and what the on- and off-rate constants of the slowly dissociating step are, the dissociation constant of the fast step ([K.
86 Ramamoorthy and Santappa (1969) (A) 'K' refers to dissociation constant of cation-chelate or solubility-product constant of solid water-insoluble compound.
These flavonols differ in the specific position of hydroxyl groups, and it could be hypothesized that a hydroxyl group sited at 5 positions on A ring and unsubstituted C2' hydroxyl group on B ring have a positive effect on the dissociation constant.
To test this hypothesis, we characterized the binding of five LC-PCB sulfates to TTR and compared their equilibrium dissociation constants (Kd values) to those determined for their hydroxylated precursors and for [T.
This change of the binding properties is quantified by a 10-fold decrease of the enzyme-substrate complex dissociation constants, which is sufficient for the generation of cooperativity of the enzyme.
It may be mentioned here that for the determination of limiting molar conductance (0) and dissociation constant (Ka) using Fuoss-Kraus equation an initial extrapolation of vs.
d]P is the probe-bilirubin dissociation constant, and [B.
3]H]PE2I from these binding data, remains within the common range of dissociation constants, characteristic of neurotransmitter antagonists in general.
where 0 is limiting molar conductance of the solute in the particular solvent at the particular temperature Ka is dissociation constant of the monobasic acid.
The calculated dissociation constant was similar to my estimated value, and the method had promise for clinical application because it directly measured the minute concentration of unbound bilirubin, which Odell's work suggested was the critical parameter for bilirubin entry into the brain.
The "true" KD represents the dissociation constant per actin monomer bound.