posterior horn

(redirected from dorsal horn)
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Related to dorsal horn: ventral horn, substantia gelatinosa, dorsal root ganglion

posterior horn

[pä¦stir·ē·ər hȯrn]
(neuroscience)
The dorsal column of gray matter in the spinal cord containing the axons of sensory (afferent) neurons.
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References in periodicals archive ?
Finally, inhibition is caused by the use of drugs that prevent the release of neurotransmitters in the dorsal horn required for pain transmission.
The effect of OMT treatment on NR2B expression was determined in the superficial dorsal horn Laminae I-III of the lumbar enlargement, areas involved in the transmission of nociceptive inputs and control of sympathetic outflow (Furst 1999).
Intravenous opioids stimulate norepinephrine and acetylcholine release in spinal cord dorsal horn.
The signal is sent by the dorsal horn to the brain, which adjusts the signal and sends it back down the spinal cord pathway).
Lowering of the stimulus threshold may occur in the synapses in the dorsal horn (central sensitisation), and continuous and intense stimulation may lead to prolonged, repeated post-synaptic depolarisation (wind-up).
Peripheral nerve endings and dorsal horn neurons in the spinal cord become sensitised, but these processes are self-limiting and resolve once the tissue has healed (Woolf & Costigan, 1999).
Aged animals (2 years old) demonstrated a decrease in the apparent number of SSeCKS fibers in the dorsal horn.
These cells are in a lower brain area called the dorsal horn of the medulla, but are comparable to cells found in the spinal cord that respond to pain elsewhere on the body.
Ford, the study showed P2X3 antagonists reduced bone cancer pain behavior by dampening down dorsal horn neuronal activity, in addition to reducing activation of extracellular-signal regulated kinase (ERK) in dorsal root ganglion (DRG) neurons.
This study confirmed our hypothesis that CPM results in significant reductions in spinal dorsal horn activity in humans," said lead study author Ian Mackey, of Stanford University in Palo Alto, Calif.
When activated, RVM neurons inhibit pain sensory processing, presumably by inhibiting the dorsal horn cells that are receiving pain information.
They travel first to the dorsal horn of the spinal cord, then from there to the brainstem, the thalamus, and then to the cerebral cortex {transmission).