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dosage compensation

   Also found in: Dictionary/thesaurus, Medical, Legal, Financial, Wikipedia 0.01 sec.
dosage compensation [′dō·sij ‚käm·pən‚sā·shən]
(genetics)
A mechanism that equalizes the expression in males and females of genes located on the X chromosome, despite their presence in two doses in the homogametic sex and a single dose in the heterogametic sex.
A mechanism that equalizes the expression of X-linked and autosomal genes by doubling the expression level of X-linked genes in maleDrosophilaand in both male and female mammals with their single active X.


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Other topics include regulation of tryptophan biosynthesis in bacillus subtilis, the molecular signatures of natural selection, switches in bacteriophage lambda development, non- homologous end joining in yeast, and chromatin remodeling in dosage compensation.
Strict dosage compensation of all genes on the chromosome isn't necessary," concludes study coauthor Laura Carrel.
Thus, the interaction between male-killer and host is not associated with somatic sex, so the target of detection and virulence is either before Sxl is produced, Sxl itself, or the dosage compensation or germ-line determination pathways.
 
 
 
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