CSH guidelines for the diagnosis and treatment of drug-induced liver injury
In recent months, the agency has seen a spike in the number of serious, potentially life- threatening health problems associated with the use of Limbrel to include drug-induced liver injury
and hypersensitivity pneumonitis.
Three publicly available drug-induced liver injury
(DILI) classification schemes were used: NCTR DILI annotation (Chen et al.
DILIsym Services provides drug-induced liver injury
simulation software and related consulting services to the pharmaceutical industry.
Overall, the most common drug associated with drug-induced liver injury
was acetaminophen (300 cases), followed by antituberculosis medications (30) and antibiotics (30).
Drug-induced liver toxicity is one of the most common adverse effects of medicines, and the protective compounds gain attention to mitigate the drug-induced liver injury
The results of the present study indicate that silymarin can prevent drug-induced liver injury
in patients being treated for tuberculosis.
Practical guidelines for diagnosis and early management of drug-induced liver injury
Genomic indicators in the blood predict drug-induced liver injury
," Pharmacogenomics Journal, vol.
This incidence of drug-induced liver injury
(DILI) accounts for 4-10% of adverse drug events (Friis and Andreasen 1992; Pillans 1996), and has become a challenging issue in the field of medicine.
Drug-induced liver injury
can have an insidious--and unpredictable--course.
Case definition and phenotype standardization in drug-induced liver injury