However, when we compared the means (SD) of the lowest results for each duplicate measurement
between the tests with and without the predilution step [no predilution, 388 (144) U/L; with predilution, 326 (111) U/L; n = 208], the lower values for the test with the predilution step were striking (Fig.
An estimate of the trueness was defined here as the degree of closeness of the mean of the participant duplicate measurements
and the target value.
The assay utilizes a polyclonal antibody sandwich assay to detect mouse sclerostin and requires 25 [micro]l of sample (serum or plasma) for duplicate measurements
In the first instance duplicate measurements
(some 55) were performed, to assess repeatability and the stability of samples at elevated temperature (see figure 4).
Precision or variability of measurements conducted under identical conditions can be obtained by duplicate measurements
a) Duplicate measurements
were made in 21 samples for PBDEs, and in 16 samples for PCBs.
of the density were made using water displacement.
Percentage differences between the means of duplicate measurements
of INR on the 2 compared instruments were calculated for each sampling time for each patient after exclusion of patients 12 and 24.
Unfortunately, it is impossible to predict whether the precision of a particular reagent lot number is acceptable because no duplicate measurements
are run routinely with POC-instruments.
These controls were performed mainly by duplicate measurements
, comparing results from self-monitoring with results obtained at the doctor's office, or use of several SMBG instruments.
The statistical analyses performed are in keeping with those recommendations, but the software neglects to provide the NCCLS-recommended scatter plot for individual test method values vs the mean of the corresponding duplicate measurements
of the comparative method.
On average, 7-10 measurement series were needed by each cRML to complete the duplicate measurements
of the frozen sera.