dynein


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dynein

[dī′nē·ən]
(cell and molecular biology)
A large enzyme complex that hydrolyzes adenosine triphosphate to provide energy to power retrograde [from (+) to (-)] transport along microtubules.
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DNHD1 (DYNC1H1) is a member of the dynein heavy chain family and is highly expressed in the brain.
Axonemal beta heavy chain dynein dnah9: Cdna sequence, genomic structure, and investigation of its role in primary ciliary dyskinesia.
Tctex2-related outer arm dynein light chain is phosphorylated at activation of sperm motility.
1996) Calcium-dependent bidirectional power stroke of the dynein arms in sea urchin sperm axonemes.
sup][13] Even, the absence of dynein arm may not necessarily be associated with ciliary immotility, and the presence of ciliary immotility might have prognostic significance as these patients appear to have more active bronchiectasis.
The disorders are characterized by ultrastructural defects in proteins in the outer or inner dynein arms of the ciliary unit.
Objective: The megadalton cytoplasmic dynein complex, whose motor subunit is encoded by a single gene, provides the major microtubule minus end-directed motility in cells and is essential for a wide range of processes, ranging from the transport of proteins, RNA, and membrane vesicles to nuclear migration and cell division.
Cell motility Intermediate filament protein Myomesin Myosin light chain Myosin 1 light chain Myosin heavy chain isoform 3 Paramyosin, short form Paramyosin, short form Tropomodulin Tropomodulin, isoform K Tropomyosin-2 isoform 1 Actin Actin Actin-2, partial Actin 4 Actin 57B Actin 88F Actin Actin E2 Alpha actinin, isoform A Beta-actin Beta-actin Beta-actin Actin 87E Actin type 1 Actin, cytoplasmic 2-like isoform 1 Alpha-tubulin Ankyrin-1-like Dynein heavy chain Stretchin-Mlck, isoform L Up-regulated during skeletal muscle growth protein 5--like Inhibitor of apoptosis protein 7.
4] Human genes: APAF1, apoptotic peptidase activating factor 1; MAP2K4, mitogen-activated protein kinase kinase 4; TP53, tumor protein p53; DLC1, deleted in liver cancer 1; NMT1, N-myristoyltransferase 1; EF2S1, eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; DYNLL1, dynein, light chain, LC8-type 1.
FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells.
RHAMM contains a centrosome targeting carboxy-terminal basic leucine zipper and, like Xklp2, interacts with the dynein motor complex (14).
Notably, earlier some cross-correlation-induced effects have been considered in the context of ratchet models in [37,38], where it has also been suggested that cross-correlation between coloured noises may provide some understanding as to why structurally very similar motor proteins with two heads, such as kinesin and dynein motor families, move in opposite directions on the micro-tubules despite sharing the same environment and experiencing the same periodicity, like with the conventional kinesin and ncd [39].