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gonadal dysgenesis |
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The prevalence of thyroid dysgenesis in iodine-sufficient regions is approximately 1 per 4,000 newborns (Fisher 1996) and has been reported to account for up to 80% of cases of congenital hypothyroidism (Foley 2000). The study sample of 37 participants includes ten persons with complete androgen insensitivity (CAIS), five with partial androgen insensitivity (PALS), four women with CAH, two women with progestogen-induced clitoromegaly, one each of Klinefelter's syndrome in a male and Turner's syndrome in a female, six miscellaneous patients including gonadal dysgenesis, micropenis, true hermaphroditism, and at least two with hypospadias, plus eight for whom the diagnosis is unknown. Alopecia universalis congenita, XY gonadal dysgenesis and laryngomalacia: A novel malformation syndrome. |
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