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Related to eastern equine encephalomyelitis: Western equine encephalitis, VEE virus


Inflammation of the brain and spinal cord.



inflammation of the brain and spinal cord as a result of infection by neurotropic viruses (acute disseminated encephalomyelitis) or as a complication of other infectious diseases, for example, measles, chicken pox, or rubella. Some cases of encephalomyelitis develop after vaccination against rabies, smallpox, and certain other diseases (postvaccinal encephalomyelitis). The inflammation may also involve the cerebrospinal roots and the peripheral nerves (encephalomyelopolyradiculoneuritis), the optic nerve or other cranial nerves (neuromyelitis optica), and the meninges (meningoencephalomyelitis).

The course of encephalomyelitis is most often acute. Symptoms include elevated body temperature, muscle pain, and various neurological symptoms (paralysis, disruption of sensitivity and motor coordination). Severe cases are marked by trophic disturbances (bedsores) and sepsis. After the acute stage, there may be residual symptoms, including paresis and disturbances of sensitivity. Treatment of encephalomyelitis is the same as for encephalitis. (See.)


Neirovirusnye infektsii. Leningrad, 1954.
Panov, A. G., and A. P. Zinchenko. Diagnostika rasseiannogo skleroza ientsefalomielita. Leningrad, 1970.




an enzootic viral disease of fur-bearing animals and swine in which the central nervous system is infected. Primarily young animals are affected. The disease occurs among fur-bearing animals in the USA and has been registered in the USSR. Teschen disease (porcine encephalomyelitis) afflicts swine in Central and Western Europe.

The causative agent of encephalomyelitis in fur-bearing animals is a neurotrophic virus; that of Teschen disease is an RNA-containing virus. Young animals are more susceptible to the disease than adults. Among fur-bearing animals, those that are afflicted include the young of foxes, including arctic foxes, and sables. Among swine, it is mainly sucklings, weaned piglets, and young being fattened that are affected.

The causative agents of the disease are introduced into the environment primarily with the saliva and nasal mucus of sick animals; in swine, it is also introduced with the feces and other excretions. Fur-bearing animals become infected through the breathing passages, while swine are infected through the respiratory and digestive tracts. The basic symptoms of the disease in fur-bearing animals include an unsteady walk, falling, convulsive attacks, the appearance of foam on the lips, and the transition from anxiety to the depressed state.

If the infection is acute, the animal dies in three to four days. Less acute cases are accompanied by a loss of appetite and diarrhea, sometimes with discharge of blood. In symptomless cases there may be abortions or the birth of nonviable young. In swine the stage of anxiety is followed by the paralysis of the extremities and of many groups of muscles. In acute cases up to 90 percent of the sick animals die; in subacute cases, up to 40 percent; and in chronic cases, up to 20 percent.

The treatment of fur bearing animals has little effect. No successful means of treating swine has been developed. In order to avoid spreading of encephalomyelitis to fur farms, animals arriving there are quarantined for one month; at swine farms the animals are inoculated with a live virus culture vaccine. When cases of the disease are discovered, and when the course of the disease is subacute, fur-bearing animals are isolated and treated with hyperimmune serum. During the winter they are slaughtered for fur. When cases of the disease are discovered in swine the entire herd is slaughtered. The meat of animals that are suspected to have the disease is processed for canning or for boiled sausage. The carcasses of sick swine or the wastes from slaughter are destroyed.

References in periodicals archive ?
Endemic eastern equine encephalomyelitis in Florida: a twenty-year analysis, 1955-1974.
Eastern equine encephalomyelitis vires in relation to the avian community of a coastal cedar swamp.
Reverse transcriptase-polymerase chain reaction (RT-PCR) primers used to sequence Eastern equine encephalomyelitis virus RNA Title Sense Primer Use Region 9930 Forward 5'-GCGCTGCTTATTTTGCTGT-3' RT-PCR E1 11582 Reverse 5'-ATTATGCGCTGCCTGTAGTGTTTA-3' RT-PCR E1 4043 Forward 5'-GTGCGCGGCGACATAACAAAGAG-3' RT-PCR NSP3 4976 Reverse 5'-CCGGGGGTACAGTGCCAGAGAA-3' RT-PCR NSP3 10470 Forward 5'-ATGCCAAACTCATCATAGGTCCACT-3' Sequencing E1 10938 Forward 5'-GTATAGCCACCGTTGCCTACAAATC-3' Sequencing E1 11345 Forward 5'-CAGGCAGTGTATAAGGCTGTCTTAC-3' Sequencing E1 T3 Forward 5'-AATTAACCCTCACTAAAGGGA-3' Sequencing NSP3 Table 2.
Louis encephalitis [SLE] and eastern equine encephalomyelitis [EEE] viruses): they are maintained in an enzootic cycle involving birds as amplifying hosts and ornithophilic mosquitoes as enzootic vectors.
This mosquito has also been hypothesized as a bridge vector for human transmission of eastern equine encephalomyelitis virus (11).

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