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ectopic expression

   Also found in: Wikipedia 0.01 sec.
ectopic expression [ek¦täp·ik iks′presh·ən]
(genetics)
Phenotypic expression of a gene in a type of cell or tissue in which it is usually inactive.


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Stimulating this receptor signal cascade through ectopic expression of this novel CD40L RNA results in secretion of the downstream inflammatory cytokine IL-12 from the electroporated DCs.
Ectopic expression of Akt induces cell survival and malignant transformation, whereas inhibition of Akt activity stimulates apoptosis in a range of mammalian cells.
In addition, the ectopic expression of the protein in endosialin/TEM1-negative cells also mediated cell-cell contact via altered cellular morphology and promoted migration of cells exposed to chemotactic stimuli, both classical characteristics of angiogenesis pathways.
 
 
 
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