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electrophilic reagent

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electrophilic reagent [i¦lek·trō¦fil·ik rē′a·jənt]
(physical chemistry)
A reactant which accepts an electron pair from a molecule, with which it forms a covalent bond.


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These compounds have resulted from the condensation-cyclization of dilithiated 2-tetralone oxime with electrophilic reagents, primarily aromatic esters, or select ketones.
It is quite different from the reaction of R and 5MR with formaldehyde and refers to the decisive factor of the reactivity of methylol electrophilic reagent on reaction rate.
While our mainstream activities have involved the preparations and reactions of the 1,4-dianions of oximes and substituted hydrazones with electrophilic reagents, such as esters and carbonyl compounds, the initial preparation of dihydronaphthisoxazoles from dilithiated 1-tetralone oxime and aromatic esters has not resulted in a routine extension to include dilithiated 1-indanone oximes, but it appears to include 1-benzosuberone hydrazones and oxime.
 
 
 
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