emetine


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emetine

[′em·ə‚tēn]
(pharmacology)
C29H40N2O4 Cephaeline methyl ether, the principal alkaloid of ipecac; a white powder, sparingly soluble in water; it is emetic, diaphoretic, and expectorant, but its chief utility is as an amebicide.
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The authors are: Tanguy Maurice (1), Vanessa Villard (1), Johann Meaner (1), Emetine Keller (1), Fanny Malaria (1), Alexandre Vamvakides (2) 1.
Laxative and toxicology screening tests were negative, but high-performance liquid chromatography revealed emetine in the urine and stool.
133-135) Some authors have suggested that critically ill patients or patients not responding to metronidazole receive emetine or chloroquine in addition to metronidazole, but these drugs have a high incidence of side effects and their use should be limited to special circumstances.
moshkovskii is osmotolerant, can be cultured at room temperature, and is resistant to emetine, all characteristics that distinguish it from E.
Taking a dosage higher than 600 mg/day of emetine for more than 10 days leads to weakness, pain, tenderness, and stiffness in limb muscles, and may cause dermatomyositislike skin changes.