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emodin

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emodin [′em·ə·dən]
(organic chemistry)
C14H4O2(OH)3CH3Orange needles crystallizing from alcohol solution, melting point 256-257°C, practically insoluble in water, soluble in alcohol and aqueous alkali hydroxide solutions, occurs as the rhamnoside in plants such as rhubarb root and alder buckthorn; used as a laxative.


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We also investigated the AhR-dependent activities of cantharidin and emodin (in herbal extracts) in Ah-responsive MCF-7 human breast cells, HepG2 human liver cancer cells, and mouse Hepa-1 cells transiently or stably transfected with plasmids expressing a luciferase reporter gene linked to multiple copies of a consensus dioxin-responsive element.
Regulation of Cell Proliferation, Inflammatory Cytokine Production and Calcium Mobilization in Primary Human T Lymphocytes by Emodin from Polygonum hypoleucum, Inflamm Res.
 
 
 
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