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enamine

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enamine [′enĀ·ə‚mēn]
(organic chemistry)
An amine in which there is a carbon-to-carbon double bond adjacent to the nitrogen, ‒C=C‒N‒; considered to be the nitrogen analog of an enol.


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Compound 3 is of interest because the exocyclic double bond is part enamine, part vinyl ether, part diene and part |A, |A-unsaturated ketone simultaneously.
Specifically, Enamine will create a compound library of kinases, which are related to cancer.
Alternatively or additionally, the Michael donor contains beta-ketoamide, enamine carboxylate, enamine amide, pyrazolone, isoxazolone, hydantoin, rhodanine, thio-substituted unsaturated ester, thio-substituted lactone or phosphonite or phosphinite ester groups.
 
 
 
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