enamine


Also found in: Dictionary, Thesaurus, Wikipedia.

enamine

[′en·ə‚mēn]
(organic chemistry)
An amine in which there is a carbon-to-carbon double bond adjacent to the nitrogen, ‒C=C‒N‒; considered to be the nitrogen analog of an enol.
References in periodicals archive ?
With the world's largest stock of chemical compounds and services, Enamine has become an important supplier at Actelion.
Under the terms of the expanded agreement, scaffold compounds supplied by Actelion will be decorated with building blocks selected from the Enamine collection to generate exclusive screening compounds by Enamine.
These ketones were synthesized by condensing the morpholine enamine of the appropriate cycloalkanone with pyridine-1-oxide in the presence of benzoyl chloride (Fig.
The benzoate is a facile leaving group, thus facilitating the acylation of the pyridine by the enamine.
Under the terms of the agreement, Enamine will provide the MRC LMB and IOCB with access to its integrated drug discovery capabilities, including Molecular Modeling, Compound Library, Screening Assays, Hit Finding and Characterization, Hit to Lead Chemistry and ADMET.
Sergey Zozulya, Vice President, Biology at Enamine, said: "We are delighted to launch this collaboration with high calibre partners, demonstrating the interest of prominent academics in realising the translational potential of their scientific discoveries through an alliance with Enamine.
Under the agreement Enamine is able to act as a single point of contact for requests from both catalogues, at no additional cost to customers.
It is conceivable that this reaction will yield either an imine (12-14), (17), (18) or an enamine (16), (21-23) or a mixture of both.
21-23), (51) Furthermore, for carbonyl compounds with an [alpha]-proton, a tautomeric equilibrium can exist between the imine and the enamine, but in which the imine form predominates.
We synthesized a series of 4-alkyl-2-(2-pyridyl)cyclohexanones using their method, which consisted of condensing morpholine enamine of the appropriate 4-alkylcyclohexanone with pyridine-1-oxide in the presence of benzoyl chloride.
We hope that this will result in a significant increase in market share for both Enamine and UORSY.
FTIR spectroscopy studies of clear films show that for hydrophilic polymers, the enamine moiety reacts with water from the atmosphere, and slowly disappears (half-life is approximately four days at room temperature), thus reforming the initial acetoacetoxy moiety and ammonia.