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enchondromatosis

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enchondromatosis [‚en‚kän·drō·mə′tō·səs]
(medicine)
A rare disorder principally involving tubular bones, especially those of the feet and hands, characterized by hamartomatous proliferation of cartilage in the metaphysis, indistinguishable in single lesions from enchondromas. Also known as chondrodysplasia; dyschondroplasia; Ollier's disease.


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Malignant change in a previously benign tumour is largely restricted to conditions such as multiple exostoses (diaphyseal aclasis) and multiple enchondromatosis or Ollier's disease, where a relatively slow-growing chondrosarcoma develops in middle age.
Differential considerations for this condition include multiple exostosis, enchondromatosis, multiple epiphyseal dysplasia, Turner's syndrome without LWD, achondroplasia, chondroectodermal dysplasia, and hypoparathyroidism.
Maffucci's syndrome is a congenital disorder characterized by multiple hemangiomas and enchondromatosis that can be present at birth or can appear during infancy or later in childhood.
 
 
 
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