Secretory component and IgA in the endolymphatic sac
tumors in von Hippel-Lindau disease.
We generated a new mutant mouse that expresses SLC26A4 in the endolymphatic sac
, but not in the cochlea or the vestibular organs of the inner ear," Wangemann said.
The pathologic findings include multiple HABs (usually retinal, cerebellar, or spinal), RCC, pheochromocytoma, islet cell tumors of the pancreas, endolymphatic sac
tumors of the inner ear, and papillary cystadenomas of the epididymis or broad ligament, as well as cysts and other benign neoplasms of the pancreas, kidney, and liver.
KEYWORDS: Endolymphatic sac
, neoplasms, hearing loss, tinnitus, dizziness
Localization of nitric oxide synthase isoforms (I, II and III) in the endolymphatic sac
of the guinea pig.
Some noted thickened capillaries in the stria vascularis, basilar membrane, and endolymphatic sac
This condition is believed to be caused by an elevated level of endolymphatic pressure, which is likely due to poor absorption from the endolymphatic sac
or excess secretion of endolymph, and results in distention of Reissner's membrane.
All except 2 cases demonstrated apical petrous temporal bone invasion on imaging, and it has been suggested that they arose from a primary endolymphatic sac
tumor, which has a similar papillary epithelial histology.
This condition resolves with either (1) the release of en dolymph through the endolymphatic sac
, (2) the reaccumulation of perilymph through the aqueduct, or (3) perhaps another mechanism.
To summarize, they are the use of the operating microscope, tympanoplasty and mastoidectomy techniques, stapes surgery, endolymphatic sac
surgery for intractable Meniere's disease, skull base surgery (for example, removal of vestibular schwannomas, vestibular nerve sections), use of intratympanic gentamycin, and cochlear implantation, not to mention the discovery of new diseases.
Patients with an endolymphatic sac
tumor (ELST) typically present with palsy of cranial nerves VII and/or VIII; other presenting symptoms include hearing loss, otalgia, occipital headaches, cranial nerve palsies, vertigo, gait ataxia, tinnitus, and otorrhea.