Malignancies such as Ewing's sarcoma and osteosarcoma typically show this pattern of involvement; however, infection and other benign processes, such as eosinophilic granulomas
(EG) (Figure 1), can have wide margins.
Solitary eosinophilic granuloma
in the frontal lobe: Case report.
Radiographic appearance of skeletal lesions simulate metastatic disease, eosinophilic granuloma
, or lymphoma.
is an uncommon condition that primarily affects children and adolescents.
as an incidental finding in malignant lymphoma.
in the head and neck: A five year review with report of an instructive case.
5) The lack of such findings ruled out Wegener's granulomatosis, Churg-Strauss syndrome, infective granulomatosis, sarcoidosis, Kimura's disease, and eosinophilic granuloma
20] Similarly, because parathyroid hormone levels have been shown to rise during clodronate-associated resolution of multifocal eosinophilic granuloma
of bone, it is unlikely that parathyroid hormone per se is responsible for the osteolytic lesions in LCH.
We also review previously reported cases of solitary eosinophilic granuloma
of the frontal bone and we discuss its clinical, radiologic, and histopathologic features.
The differential diagnosis of fibro-osseous lesions of the temporal bone includes fibrous dysplasia, meningioma, aneurysmal bone cyst, unicameral cyst, ossifying or nonossifying fibroma, Paget's disease, osteochondroma, giant cell tumor, eosinophilic granuloma
exostosis, osteoma, and sarcomatous neoplasms.
mansoni ova within large eosinophilic granulomas
, consistent with tumoral neuroschistosomiasis.
3) The following can also be observed: proteinaceous deposits in germinal centers, vascularization of germinal centers (Figure 1), necrosis of germinal centers, polykaryocytes (Warthin-Finkeldey-type giant cells), eosinophils in germinal centers, eosinophilic folliculolysis, eosinophilic microabscesses, postcapillary venule proliferation, stromal sclerosis, perivenular sclerosis, rare giant cells (Warthin-Finkeldey-type giant cells), or small eosinophilic granulomas