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Epistasis
(redirected from epistatic)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
epistasis [ə′pis·tə·səs]
(genetics)
The suppression of the effect of one gene by another.
(medicine)
A checking or stoppage of a hemorrhage or other discharge.
(pathology)
A scum or film of substance floating on the surface of urine.
Epistasis 

the interaction of two nonallelic genes (that is, genes that are at different loci) whereby one of them, called the epistatic gene, suppresses the effect of the other one, called the hypostatic gene. Phenotypically, epistasis is manifested as a deviation from the segregation that would be expected in digenetic inheritance; in this case, however, there is no violation of Mendel’s laws, inasmuch as the alleles of the interacting genes are distributed in complete conformity to the law of independent assortment, or combination.
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Epistatic Epistatic genetic variance is also produced by interactions among alleles but at different loci rather than at the same locus.
Genetic aspects of restoring Olympia oysters and other native ... by Camara, Mark D.; Vadopalas, Brent / Journal of Shellfish Research
20) However, the APOE [epsilon]4 allele is neither necessary nor sufficient to cause the disease, indicating epistatic or epigenetic mechanisms.
Alzheimer's disease: new perspectives on integration of ... by Moghaddam, Mojdeh; Yen, Yung-Chieh; Gross, Alden L.; Rebok, George W. / Journal of Medical Psychology
Identifying specific genes is further complicated by incomplete penetrance, pleiotropy (multiple effects of a single gene), and epistatic interactions (several genes interacting in the same individuals) [115].
Posttraumatic stress disorder and posttraumatic stress disorder-like ... by Kennedy, Jan E.; Jaffee, Michael S.; Leskin, Gregory A.; Stokes, James W.; Leal, Felix O.; Fitzpatri / Journal of Rehabilitation Research & Development
 
 
 
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