Think of Lofgren's syndrome in patients with symmetrical ankle inflammation or erythema nodosum
A case of granulomatous mastitis with erythema nodosum
So, it can be concluded from the discussion that the erythema nodosum
leprosum presenting as vesiculopustuloulcerative lesions as initial manifestation of leprosy, although is very uncommon, can present as acute febrile illness manifesting as erythematous tender nodules and plaques over extremities, trunk, and other body parts.
It is important to note that the cutaneous lesions may be secondary to the fungal infection or due to a hypersensitivity reaction to the pulmonary infection, which commonly presents as erythema nodosum
Patients undergoing treatment must be monitored for immunologic complications, such as cell-mediated reversal reaction (type 1 reaction) or interferon-[alpha]-mediated erythema nodosum
leprosum (type 2 reaction).
is the most frequent form of panniculitis (inflammation of the subcutaneous fat) and may be caused by a wide variety of stimuli, including infection, medications, systemic illnesses such as sarcoidosis, and malignancy.
6) Erythema nodosum
can be present in sarcoidosis, but may also be present as a manifestation of drug reactions, malignancies, and infectious etiologies.
is the most common type of panniculitis.
The patients' ages, duration of the disease, family history, presence of oral ulcers, genital ulcers, erythema nodosum
, acneiform eruptions, epididymitis, arthralgia and arthritis, and vascular, pulmonary, gastrointestinal, neurological, and ophthalmic involvement were recorded.
The tests directed to the possible underlying causes performed in the patient whose skin lesions were evaluated as erythema nodosum
, who had a previous history of diarrhea, prolonged fever and arthritis findings were as follows: salmonella and brucella serology (-), viral tests: HBs Ag (-), antiHBs (+), cytomegalovirus (CMV) IgM (+), CMV IgG (+), CMV PCR (-), high positive CMV avidity, normal serum immunoglubulins and complements levels, p-ANCA (-), HLAB5 (-), antinuclear antibody (-), antidsDNA (-) and rheumatoid factor (-).
People with ulcerative colitis often have other disorders including arthritis, causing pain in the joints, and ankylosing spondylitis, causing pain in the spine, inflammation of the eye (uveitis), and the skin condition erythema nodosum
It is important to identify Lofgren's syndrome (consisting of erythema nodosum
, bilateral hilar adenopathy, migratory polyarthritis and fever), as not only does it have a good prognosis, but it is also made without the need for histological proof.