erythromycin


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erythromycin

(ĭrĭth'rōmī`sĭn), any of several related antibiotic drugs produced by bacteria of the genus Streptomyces (see antibioticantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
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). Erythromycin is most effective against gram-positive bacteria such as pneumococci, streptococci, and some staphylococci (see Gram's stainGram's stain,
laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls. The Gram stain, named after its developer, Danish bacteriologist Christian Gram, has become an important tool
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). The antibiotic also has some effect on gram-negative bacteria and some fungi. Erythromycin inhibits protein synthesis in susceptible microorganisms. It is used to treat such diseases as pneumonia caused by fungi, and streptococcus and syphilis infections, especially where the patient is allergic to penicillin.

Erythromycin

 

a macrolide antibiotic, the chief producer of which is the soil-inhabiting organism Streptomyces erythreus. Erythromycin is active against most grampositive bacteria (such as staphylococci, streptococci, and pneumococci), certain gram-negative bacteria (such as brucellae), rickettsiae, and large viruses. It fights staphylococci that are resistant to penicillin, antibiotics of the tetracycline group, and streptomycin. Erythromycin is used for treating pneumonia and other infectious diseases.

erythromycin

[ə‚rith·rə′mīs·ən]
(microbiology)
A crystalline antibiotic produced by Streptomyces erythreus and used in the treatment of gram-positive bacterial infections.
References in periodicals archive ?
Erythromycin enhances gastrointestinal motor activity in a dose-dependent manner
Most importantly similar behaviours were observed among strains, regardless of their susceptibility to erythromycin or clindamycin according to MIC/MBC (Table 1) determination.
Clinical relapse and development of resistance to clindamycin, lincosamide and erythromycin.
pumilus to erythromycin has been observed in in vitro studies of Adewumi et al.
8%) had 2 or 3 erythromycin resistance determinants, and the combination ermB/mefA/E was predominantly found in 26.
Meanwhile, 2 patients refused from continuing the trial, as they did not like to use erythromycin due to undesirable smell and stinging sensation.
50] values for erythromycin and telithromycin were 794 and 126 [micro]g/ml and for clarithromycin it was above than the highest level/ concentration tested (119 [micro]g/ml) (Fig.
4% of the erythromycin resistance to be caused by the constitutive [MLS.
The studies evaluated the use of amoxicillin-clavulanate 375 mg and/or erythromycin 250 mg in women presenting with preterm rupture of membranes (ORACLE I) or in spontaneous preterm labor (ORACLE II).
All 11 had been treated at children's hospital A with erythromycin and recovered; none developed hypertrophic pyloric stenosis, which has been reported as a complication of treatment of infants with erythromycin (2).
At the time of this study, 26% of all GBS isolates at Brown were resistant to clindamycin; 37% were resistant to erythromycin.