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exon shuffling

   Also found in: Wikipedia 0.01 sec.
exon shuffling [′ek‚sän ‚shəf·liŋ]
(genetics)
In eukaryotic split genes, the creation of new genes by the addition or removal of exons through unequal crossing over within introns intervening between the exons of a split gene.


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for selective ligation of certain molecules within a collection of molecules), and also for methods of exon shuffling, in which multiple different product molecules are produced in a single ligation reaction.
I do not discuss the mechanics of gene duplication or exon shuffling which are the main means by which new molecules arise (Graur and Li, 2000).
Thus, the finding contradicts the view that introns are evolutionary relics that are removed because they serve no purpose The work supports the exon shuffling theory, which contends that introns act as spacers where breaks for genetic recombination occur.
 
 
 
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