extracellular matrix


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extracellular matrix

[¦ek·strə¦sel·yə·lər ′mā·triks]
(cell and molecular biology)
A filamentous structure that is attached to the outer cell surface and provides anchorage, traction, and positional recognition to the cell.
(histology)
A filamentous structure of glycoproteins and proteoglycans that is attached to the cell surface and provides cells with anchorage, traction for movement, and positional recognition. Abbreviated ECM.
References in periodicals archive ?
Under normal circumstances, fat cells continue to grow until they reach a point where the extracellular matrix they've built around themselves is so strong that it's no longer flexible.
Indeed, investigators have found that cells from very different organs and tissues become almost indistinguishable when removed from their normal extracellular matrix and placed on glass or plastic surfaces.
Our data provide the first evidence that a selected population of marrow cells can connect the epidermis and dermis in a mouse model of the disease and offer a potentially valuable approach for treatment of human RDEB and other extracellular matrix disorders.
Osteocalcin is the most abundant of several noncollagen proteins in the extracellular matrix of bone.
To examine just how this extracellular matrix affects the cells attached to it, biologists are growing cells on laboratory plates, where the cell's semisolid support and surrounding solution can be manipulated directly.

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